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Devbiology - COBRE

Developmental Biology in Oklahoma

Expanding Excellence in Developmental Biology in Oklahoma Center of Biomedical Research Excellence (COBRE)

  • Welcome
  • Administrative Core
    • Internal Advisory Committee
    • External Advisory Committee
  • Current Projects
    • Notch regulation of COPD-associated goblet cell hyperplasia/metaplasia
    • Mechanistic insights into how the pBAF complex influences chromatin structure
    • Determining the mechanistic effects of the sas-6(L69T) mutation in C. elegans
  • Former Projects
  • Cores
    • Bioinformatics and Pathways Core
    • Imaging Core

Former Projects

Phase 1 Graduates

Hui-Ying Lim, Ph.D.
Associate Professor of Physiology, University of Oklahoma Health Sciences Center
“Reactive oxygen species in the epi/pericardium regulate Drosophila heart physiology“

Lorin Olson, Ph.D.
Associate Member, Cardiovascular Biology Program, OMRF
“Understanding connective tissue development and disease with PDGFR-driven models of fibrosis”

Roberto Pezza, Ph.D.
Associate Member, Cell Cycle and Cancer Biology Program, OMRF
“The roles of Hop2 and Mnd1 in mouse meiotic homologous recombination.”

Chris Sansam, Ph.D.
Associate Member, Cell Cycle and Cancer Biology Program, OMRF
“TopBP1 and TICRR in the chemotherapy response and embryonic development”

Weidong Wang, Ph.D.
Associate Professor of Medicine, Endocrinology & Diabetes
William K. Warren, Sr. Chair in Diabetes Studies
“Derivation of pancreatic beta cells from human induced pluripotent stem cells”

Phase 2 Graduates

David Forsthoefel, Ph.D.
Assistant Member, Genes & Human Disease, OMRF
“Non-autonomous regulation of stem cell proliferation during regeneration” 

Jian Li, Ph.D.
Assistant Professor of Cell Biology & Anatomy, New York Medical College
“Spatiotemporal regulation of stress-responsive transcription factors in organismal aging”

Gaurav Varshney, Ph.D.
Assistant Member, Genes & Human Disease, OMRF
“Functional genomics of hearing loss genes in zebrafish”

Wan Hee Yoon, Ph.D.
Assistant Member, Aging & Metabolism, OMRF
“Unraveling mechanisms for neurological diseases caused by ATAD3A mutations”

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  • Welcome
  • Administrative Core
    • Internal Advisory Committee
    • External Advisory Committee
  • Current Projects
    • Notch regulation of COPD-associated goblet cell hyperplasia/metaplasia
    • Mechanistic insights into how the pBAF complex influences chromatin structure
    • Determining the mechanistic effects of the sas-6(L69T) mutation in C. elegans
  • Former Projects
  • Cores
    • Bioinformatics and Pathways Core
    • Imaging Core